1. Claudication – a cramping sensation in the buttocks, thighs, or calves. Treatments include medical therapies, lifestyle modifications, smoking cessation, exercise, and, in rare circumstances, surgery. 2. Rest Pain – a burning or throbbing pain in the foot, often worse at night when trying to sleep. This can be a sign of impending, permanent damage to the leg. A referral to our vascular surgery team is important so that a proper workup can be performed. 3. Ulceration/Gangrene – ulcers on the toes and/or feet that do not heal within two weeks. Severely damaged blood flow may lead to ulcers that do not have enough oxygen or nutrients to form new skin. https://symmetryvascular.com